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ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells

BACKGROUND: The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT) participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular oxygen tension. In hypoxia, HIF-1α and ARNT form the transcriptional active complex HIF-1 followed by the expressio...

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Detalles Bibliográficos
Autores principales: Mandl, Markus, Depping, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571568/
https://www.ncbi.nlm.nih.gov/pubmed/28855849
http://dx.doi.org/10.1186/s12935-017-0446-2