Protein–ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation

Serial femtosecond crystallography (SFX) with an X-ray free-electron laser is used for the structural determination of proteins from a large number of microcrystals at room temperature. To examine the feasibility of pharmaceutical applications of SFX, a ligand-soaking experiment using thermolysin mi...

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Detalles Bibliográficos
Autores principales: Naitow, Hisashi, Matsuura, Yoshinori, Tono, Kensuke, Joti, Yasumasa, Kameshima, Takashi, Hatsui, Takaki, Yabashi, Makina, Tanaka, Rie, Tanaka, Tomoyuki, Sugahara, Michihiro, Kobayashi, Jun, Nango, Eriko, Iwata, So, Kunishima, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571745/
https://www.ncbi.nlm.nih.gov/pubmed/28777085
http://dx.doi.org/10.1107/S2059798317008919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571745/
https://www.ncbi.nlm.nih.gov/pubmed/28777085
http://dx.doi.org/10.1107/S2059798317008919

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