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Could clinical photochemical internalisation be optimised to avoid neuronal toxicity?

Photochemical Internalisation (PCI) is a novel drug delivery technology in which low dose photodynamic therapy (PDT) can selectively rupture endo/lysosomes by light activation of membrane-incorporated photosensitisers, facilitating intracellular drug release in the treatment of cancer. For PCI to be...

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Detalles Bibliográficos
Autores principales: O’Rourke, Caitriona, Hopper, Colin, MacRobert, Alexander J., Phillips, James B., Woodhams, Josephine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571751/
https://www.ncbi.nlm.nih.gov/pubmed/28579544
http://dx.doi.org/10.1016/j.ijpharm.2017.05.071