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A Trp53(fl/fl)Pten(fl/fl) mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging

Genetic mouse models of soft tissue sarcoma provide critical insights into disease pathophysiology, which are oftentimes unable to be extracted from human tumor samples or xenograft models. In this study we describe a mouse model of soft tissue sarcoma mediated by adenoviral-Cre recombinase injectio...

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Detalles Bibliográficos
Autores principales: Buchakjian, Marisa R., Merritt, Nicole M., Moose, Devon L., Dupuy, Adam J., Tanas, Munir R., Henry, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571905/
https://www.ncbi.nlm.nih.gov/pubmed/28841687
http://dx.doi.org/10.1371/journal.pone.0183469