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Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer
ROCK, or Rho-associated coiled coil-containing protein kinase, is a member of the AGC kinase family and has been shown to play a role in cell migration, ECM synthesis, stress-fiber assembly, and cell contraction. Increased ROCK expression has been reported in multiple pathological conditions, includ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571985/ https://www.ncbi.nlm.nih.gov/pubmed/28841710 http://dx.doi.org/10.1371/journal.pone.0183871 |