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α4-integrin receptor desaturation and disease activity return after natalizumab cessation

OBJECTIVE: To describe the time course of α4-integrin receptor desaturation and disease activity return in patients with relapsing-remitting MS who discontinued natalizumab and to investigate baseline and on-study predictors for the recurrence of disease activity. METHODS: In the course of TOFINGO,...

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Detalles Bibliográficos
Autores principales: Derfuss, Tobias, Kovarik, John M., Kappos, Ludwig, Savelieva, Marina, Chhabra, Richa, Thakur, Avinash, Zhang, Ying, Wiendl, Heinz, Tomic, Davorka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572051/
https://www.ncbi.nlm.nih.gov/pubmed/28856176
http://dx.doi.org/10.1212/NXI.0000000000000388