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Epigenetic response of imprinted domains during carcinogenesis

BACKGROUND: Imprinted domains have been identified as targets for aberrant DNA methylation during carcinogenesis, but it remains unclear when these epigenetic alterations occur and how they contribute to tumor progression. Epigenetic instability at key cis-regulatory elements within imprinted domain...

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Detalles Bibliográficos
Autores principales: Bretz, Corey L., Langohr, Ingeborg M., Kim, Joomyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572065/
https://www.ncbi.nlm.nih.gov/pubmed/28855972
http://dx.doi.org/10.1186/s13148-017-0393-8