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Epigenetic response of imprinted domains during carcinogenesis
BACKGROUND: Imprinted domains have been identified as targets for aberrant DNA methylation during carcinogenesis, but it remains unclear when these epigenetic alterations occur and how they contribute to tumor progression. Epigenetic instability at key cis-regulatory elements within imprinted domain...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572065/ https://www.ncbi.nlm.nih.gov/pubmed/28855972 http://dx.doi.org/10.1186/s13148-017-0393-8 |