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Guanidine N-methylation by BlsL Is Dependent on Acylation of Beta-amine Arginine in the Biosynthesis of Blasticidin S

The peptidyl nucleoside blasticidin S (BS) produced by Streptomyces griseochromogenes was the first non-mercurial fungicide used to prevent rice blast and increasingly used as a selection reagent in transgenic study. Acylation by addition of a leucine residue at the beta amine group of arginine side...

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Detalles Bibliográficos
Autores principales: Wang, Xiankun, Du, Aiqin, Yu, Guiyang, Deng, Zixin, He, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572114/
https://www.ncbi.nlm.nih.gov/pubmed/28878744
http://dx.doi.org/10.3389/fmicb.2017.01565