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Guanidine N-methylation by BlsL Is Dependent on Acylation of Beta-amine Arginine in the Biosynthesis of Blasticidin S
The peptidyl nucleoside blasticidin S (BS) produced by Streptomyces griseochromogenes was the first non-mercurial fungicide used to prevent rice blast and increasingly used as a selection reagent in transgenic study. Acylation by addition of a leucine residue at the beta amine group of arginine side...
Autores principales: | Wang, Xiankun, Du, Aiqin, Yu, Guiyang, Deng, Zixin, He, Xinyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572114/ https://www.ncbi.nlm.nih.gov/pubmed/28878744 http://dx.doi.org/10.3389/fmicb.2017.01565 |
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