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Distinct unfolded protein responses mitigate or mediate effects of nonlethal deprivation of C. elegans sleep in different tissues

BACKGROUND: Disrupting sleep during development leads to lasting deficits in chordates and arthropods. To address lasting impacts of sleep deprivation in Caenorhabditis elegans, we established a nonlethal deprivation protocol. RESULTS: Deprivation triggered protective insulin-like signaling and two...

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Detalles Bibliográficos
Autores principales: Sanders, Jarred, Scholz, Monika, Merutka, Ilaria, Biron, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572162/
https://www.ncbi.nlm.nih.gov/pubmed/28844202
http://dx.doi.org/10.1186/s12915-017-0407-1