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RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer

BACKGROUND: The transforming growth factor-β (TGF-β) pathway plays a vital role in driving cancer cell epithelial–mesenchymal transition (EMT). Zonula occludens-1 (ZO-1), which is downregulated in response to TGF-β, is able to control endothelial cell–cell tension, cell migration, and barrier format...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Zhou, Xu-Jie, Sun, Xi, Xia, Tian-Song, Li, Xiao-Xia, Shi, Liang, Zhu, Lei, Zhou, Wen-Bin, Wei, Ji-Fu, Ding, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572167/
https://www.ncbi.nlm.nih.gov/pubmed/28683467
http://dx.doi.org/10.1038/bjc.2017.204