HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer

BACKGROUND: Pancreatic cancer is currently the third leading cause of cancer deaths in the United States and it is predicted to become the second by the year 2030. High-mobility group A1 protein (HMGA1) is an oncogenic transcription factor, localised and active in cell nuclei, that is linked to tumo...

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Detalles Bibliográficos
Autores principales: Veite-Schmahl, Michelle J, Joesten, William C, Kennedy, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572173/
https://www.ncbi.nlm.nih.gov/pubmed/28697176
http://dx.doi.org/10.1038/bjc.2017.216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572173/
https://www.ncbi.nlm.nih.gov/pubmed/28697176
http://dx.doi.org/10.1038/bjc.2017.216

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