DNA Delivery and Genomic Integration into Mammalian Target Cells through Type IV A and B Secretion Systems of Human Pathogens

We explore the potential of bacterial secretion systems as tools for genomic modification of human cells. We previously showed that foreign DNA can be introduced into human cells through the Type IV A secretion system of the human pathogen Bartonella henselae. Moreover, the DNA is delivered covalent...

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Detalles Bibliográficos
Autores principales: Guzmán-Herrador, Dolores L., Steiner, Samuel, Alperi, Anabel, González-Prieto, Coral, Roy, Craig R., Llosa, Matxalen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572225/
https://www.ncbi.nlm.nih.gov/pubmed/28878740
http://dx.doi.org/10.3389/fmicb.2017.01503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572225/
https://www.ncbi.nlm.nih.gov/pubmed/28878740
http://dx.doi.org/10.3389/fmicb.2017.01503

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