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Comparative Analysis of 3D Bladder Tumor Spheroids Obtained by Forced Floating and Hanging Drop Methods for Drug Screening

Introduction: Cell-based assays using three-dimensional (3D) cell cultures may reflect the antitumor activity of compounds more accurately, since these models reproduce the tumor microenvironment better. Methods: Here, we report a comparative analysis of cell behavior in the two most widely employed...

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Detalles Bibliográficos
Autores principales: Amaral, Robson L. F., Miranda, Mariza, Marcato, Priscyla D., Swiech, Kamilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572239/
https://www.ncbi.nlm.nih.gov/pubmed/28878686
http://dx.doi.org/10.3389/fphys.2017.00605