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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that results from the loss of upper and lower motor neurons. One of the key pathological hallmarks in diseased neurons is the mislocalization of disease-associated proteins and the formation of cytoplasmic aggregates of these protei...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572252/ https://www.ncbi.nlm.nih.gov/pubmed/28878620 http://dx.doi.org/10.3389/fnmol.2017.00263 |