Increased Potency of a Bi-specific TL1A-ADAM17 (TACE) Inhibitor by Cell Surface Targeting

Inflammatory bowel disease (IBD) is a multifactorial disease characterized by the dysregulated activity of many pro-inflammatory factors. Thus, bi-specific inhibitors for the simultaneous inhibition of two pro-inflammatory factors can exhibit high therapeutic potential. Here, we developed a novel bi...

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Detalles Bibliográficos
Autores principales: Weizman, Tomer, Levin, Itay, Zaretsky, Marianna, Sagi, Irit, Aharoni, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572276/
https://www.ncbi.nlm.nih.gov/pubmed/28879185
http://dx.doi.org/10.3389/fmolb.2017.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572276/
https://www.ncbi.nlm.nih.gov/pubmed/28879185
http://dx.doi.org/10.3389/fmolb.2017.00061

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