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P2Y(6) Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and very few available treatment options. The involvement of the purinergic receptor subtypes P2Y(2) and P2X(7) in fibrotic lung disease has been demonstrated recently. In this study, we investigated the role of P2Y(6) receptors...

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Detalles Bibliográficos
Autores principales: Müller, Tobias, Fay, Susanne, Vieira, Rodolfo Paula, Karmouty-Quintana, Harry, Cicko, Sanja, Ayata, Cemil Korcan, Zissel, Gernot, Goldmann, Torsten, Lungarella, Giuseppe, Ferrari, Davide, Di Virgilio, Francesco, Robaye, Bernard, Boeynaems, Jean-Marie, Lazarowski, Eduardo R., Blackburn, Michael R., Idzko, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572280/
https://www.ncbi.nlm.nih.gov/pubmed/28878780
http://dx.doi.org/10.3389/fimmu.2017.01028