Cargando…

P2Y(6) Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and very few available treatment options. The involvement of the purinergic receptor subtypes P2Y(2) and P2X(7) in fibrotic lung disease has been demonstrated recently. In this study, we investigated the role of P2Y(6) receptors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Müller, Tobias, Fay, Susanne, Vieira, Rodolfo Paula, Karmouty-Quintana, Harry, Cicko, Sanja, Ayata, Cemil Korcan, Zissel, Gernot, Goldmann, Torsten, Lungarella, Giuseppe, Ferrari, Davide, Di Virgilio, Francesco, Robaye, Bernard, Boeynaems, Jean-Marie, Lazarowski, Eduardo R., Blackburn, Michael R., Idzko, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572280/ https://www.ncbi.nlm.nih.gov/pubmed/28878780 http://dx.doi.org/10.3389/fimmu.2017.01028

Ejemplares similares

The purinergic receptor subtype P2Y(2) mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease
por: Müller, Tobias, et al.
Publicado: (2017)

Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosis
por: Cicko, Sanja, et al.
Publicado: (2015)

Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
por: Cicko, Sanja, et al.
Publicado: (2018)

P2rx4 deficiency in mice alleviates allergen-induced airway inflammation
por: Zech, Andreas, et al.
Publicado: (2016)

P2Y2R Signaling Is Involved in the Onset of Glomerulonephritis
por: Rennert, Laura, et al.
Publicado: (2018)

CD39 is a negative regulator of P2X7-mediated inflammatory cell death in mast cells
por: Kuhny, Marcel, et al.
Publicado: (2014)

Prevention of M2 polarization and temporal limitation of differentiation in monocytes by extracellular ATP
por: Scherr, Benedikt F., et al.
Publicado: (2023)

Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33
por: Calvén, Jenny, et al.
Publicado: (2015)

AMP Affects Intracellular Ca(2+) Signaling, Migration, Cytokine Secretion and T Cell Priming Capacity of Dendritic Cells
por: Panther, Elisabeth, et al.
Publicado: (2012)

5-Hydroxytryptamine Modulates Migration, Cytokine and Chemokine Release and T-Cell Priming Capacity of Dendritic Cells In Vitro and In Vivo
por: Müller, Tobias, et al.
Publicado: (2009)

Crystal Deposits in Macrophages and Distal Lung Remodeling: A Tale of Aging in SFTPC-Deficient Mice
por: Weng, Tingting, et al.
Publicado: (2020)

CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II
por: Pechkovsky, Dmitri V, et al.
Publicado: (2005)

Enhancement of Glucose Uptake in Mouse Skeletal Muscle Cells and Adipocytes by P2Y(6) Receptor Agonists
por: Balasubramanian, Ramachandran, et al.
Publicado: (2014)

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
por: Goldmann, Torsten, et al.
Publicado: (2018)

Role of purinergic signaling in experimental pneumococcal meningitis
por: Zierhut, Marco, et al.
Publicado: (2017)

Interleukin-6 Contributes to Inflammation and Remodeling in a Model of Adenosine Mediated Lung Injury
por: Pedroza, Mesias, et al.
Publicado: (2011)

Time course of airway remodelling after an acute chlorine gas exposure in mice
por: Tuck, Stephanie A, et al.
Publicado: (2008)

Disruption of the Microglial ADP Receptor P2Y(13) Enhances Adult Hippocampal Neurogenesis
por: Stefani, Jennifer, et al.
Publicado: (2018)

Metabolite-Sensing G Protein-Coupled Receptors Connect the Diet-Microbiota-Metabolites Axis to Inflammatory Bowel Disease
por: Melhem, Hassan, et al.
Publicado: (2019)

Protective Role of P2Y(2) Receptor against Lung Infection Induced by Pneumonia Virus of Mice
por: Vanderstocken, Gilles, et al.
Publicado: (2012)

P2Y(2)R Deficiency Attenuates Experimental Autoimmune Uveitis Development
por: Relvas, Lia Judice M., et al.
Publicado: (2015)

Snakes and Ladders: A Potential Therapy of Hepatocyte Growth Factor and Pigment Epithelium-derived Factor in Pulmonary Hypertension
por: Zambelas, Joseph M., et al.
Publicado: (2023)

The Copper/Zinc Ratio Correlates With Markers of Disease Activity in Patients With Inflammatory Bowel Disease
por: Schneider, Tobias, et al.
Publicado: (2020)

Adenosine promotes vascular barrier function in hyperoxic lung injury
por: Davies, Jonathan, et al.
Publicado: (2014)

Acute lung affection in an endurance-trained man under amiodarone medication
por: Walterspacher, Stephan, et al.
Publicado: (2005)

Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension
por: Goel, Khushboo, et al.
Publicado: (2022)

Lack of P2Y(13) in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport
por: Lichtenstein, Laeticia, et al.
Publicado: (2013)

P2X(7) receptor: Death or life?
por: Adinolfi, Elena, et al.
Publicado: (2005)

Niveaux d'aspiration et d'expectation : criteres de personalité
por: Robaye, Francine
Publicado: (1957)

Enhancing Extracellular Adenosine Levels Restores Barrier Function in Acute Lung Injury Through Expression of Focal Adhesion Proteins
por: Wang, Wei, et al.
Publicado: (2021)

Hyaluronan in the pathogenesis of acute and post-acute COVID-19 infection
por: Barnes, Henry W., et al.
Publicado: (2023)

Editorial: Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction
por: Karmouty-Quintana, Harry, et al.
Publicado: (2018)

Mechanisms of Pulmonary Hypertension in Acute Respiratory Distress Syndrome (ARDS)
por: Revercomb, Lucy, et al.
Publicado: (2021)

Nanotherapeutics for Treatment of Pulmonary Arterial Hypertension
por: Segura-Ibarra, Victor, et al.
Publicado: (2018)

Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung
por: Schultz, H, et al.
Publicado: (2011)

Serum Level of CC-Chemokine Ligand 18 Is Increased in Patients with Non-Small-Cell Lung Cancer and Correlates with Survival Time in Adenocarcinomas
por: Plönes, Till, et al.
Publicado: (2012)

CC-Chemokine Ligand 18 Induces Epithelial to Mesenchymal Transition in Lung Cancer A549 Cells and Elevates the Invasive Potential
por: Ploenes, Till, et al.
Publicado: (2013)

Lung Collagens Perpetuate Pulmonary Fibrosis via CD204 and M2 Macrophage Activation
por: Stahl, Mirjam, et al.
Publicado: (2013)

Chromatin Remodelers: From Function to Dysfunction
por: Längst, Gernot, et al.
Publicado: (2015)

The emerging role of NOTCH3 receptor signalling in human lung diseases
por: Bodas, Manish, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uq5dqbtbrnisg3f55p1kko7fn0