Natural IgM and TLR Agonists Switch Murine Splenic Pan-B to “Regulatory” Cells That Suppress Ischemia-Induced Innate Inflammation via Regulating NKT-1 Cells

Natural IgM anti-leukocyte autoantibodies (IgM-ALAs) inhibit inflammation by several mechanisms. Here, we show that pan-B cells and bone marrow-derived dendritic cells (BMDCs) are switched to regulatory cells when pretreated ex vivo with IgM. B cells are also switched to regulatory cells when pretre...

Descripción completa

Detalles Bibliográficos
Autores principales: Lobo, Peter I., Schlegel, Kailo H., Bajwa, Amandeep, Huang, Liping, Okusa, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572342/
https://www.ncbi.nlm.nih.gov/pubmed/28878768
http://dx.doi.org/10.3389/fimmu.2017.00974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572342/
https://www.ncbi.nlm.nih.gov/pubmed/28878768
http://dx.doi.org/10.3389/fimmu.2017.00974

Ejemplares similares