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Item Response Theory to Quantify Longitudinal Placebo and Paliperidone Effects on PANSS Scores in Schizophrenia

As biomarkers are lacking, multi‐item questionnaire‐based tools like the Positive and Negative Syndrome Scale (PANSS) are used to quantify disease severity in schizophrenia. Analyzing composite PANSS scores as continuous data discards information and violates the numerical nature of the scale. Here...

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Detalles Bibliográficos
Autores principales: Krekels, EHJ, Novakovic, AM, Vermeulen, AM, Friberg, LE, Karlsson, MO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572362/
https://www.ncbi.nlm.nih.gov/pubmed/28571119
http://dx.doi.org/10.1002/psp4.12207