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Identification of the Tolfenamic Acid Binding Pocket in PrbP from Liberibacter asiaticus

In Liberibacter asiaticus, PrbP is an important transcriptional accessory protein that was found to regulate gene expression through interactions with the RNA polymerase β-subunit and a specific sequence on the promoter region. It was found that inactivation of PrbP, using the inhibitor tolfenamic a...

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Detalles Bibliográficos
Autores principales: Pan, Lei, Gardner, Christopher L., Pagliai, Fernando A., Gonzalez, Claudio F., Lorca, Graciela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572369/
https://www.ncbi.nlm.nih.gov/pubmed/28878750
http://dx.doi.org/10.3389/fmicb.2017.01591