Development of Physiologically Based Organ Models to Evaluate the Pharmacokinetics of Drugs in the Testes and the Thyroid Gland

We extended a generic whole‐body physiologically based pharmacokinetic (PBPK) model for rats and humans for organs of the reproductive and endocrine systems (i.e., the testes and the thyroid gland). An extensive literature search was performed, first, to determine the most generic organ model struct...

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Detalles Bibliográficos
Autores principales: Pilari, S, Gaub, T, Block, M, Görlitz, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572381/
https://www.ncbi.nlm.nih.gov/pubmed/28571120
http://dx.doi.org/10.1002/psp4.12205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572381/
https://www.ncbi.nlm.nih.gov/pubmed/28571120
http://dx.doi.org/10.1002/psp4.12205

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