A20/TNFAIP3 Discriminates Tumor Necrosis Factor (TNF)-Induced NF-κB from JNK Pathway Activation in Hepatocytes

In the liver tumor necrosis factor (TNF)-induced signaling critically regulates the immune response of non-parenchymal cells as well as proliferation and apoptosis of hepatocytes via activation of the NF-κB and JNK pathways. Especially, the induction of negative feedback regulators, such as IκBα and...

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Detalles Bibliográficos
Autores principales: Pinna, Federico, Bissinger, Michaela, Beuke, Katharina, Huber, Nicolas, Longerich, Thomas, Kummer, Ursula, Schirmacher, Peter, Sahle, Sven, Breuhahn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572400/
https://www.ncbi.nlm.nih.gov/pubmed/28878689
http://dx.doi.org/10.3389/fphys.2017.00610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572400/
https://www.ncbi.nlm.nih.gov/pubmed/28878689
http://dx.doi.org/10.3389/fphys.2017.00610

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