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Dipyridamole potentiated the trypanocidal effect of nifurtimox and improved the cardiac function in NMRI mice with acute chagasic myocarditis

BACKGROUND: As chronic Chagas disease does not have a definitive treatment, the development of alternative therapeutic protocols is a priority. Dipyridamole (DPY) is an alternative to counteract the pathophysiological phenomena involved in Chagas cardiomyopathy. OBJECTIVE: To evaluate the therapeuti...

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Detalles Bibliográficos
Autores principales: Santeliz, Sonia, Caicedo, Peter, Giraldo, Elidiosmar, Alvarez, Carmen, Yustiz, María-Daniela, Rodríguez-Bonfante, Claudina, Bonfante-Rodríguez, Romina, Bonfante-Cabarcas, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572445/
https://www.ncbi.nlm.nih.gov/pubmed/28902285
http://dx.doi.org/10.1590/0074-02760160499