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Dipyridamole potentiated the trypanocidal effect of nifurtimox and improved the cardiac function in NMRI mice with acute chagasic myocarditis
BACKGROUND: As chronic Chagas disease does not have a definitive treatment, the development of alternative therapeutic protocols is a priority. Dipyridamole (DPY) is an alternative to counteract the pathophysiological phenomena involved in Chagas cardiomyopathy. OBJECTIVE: To evaluate the therapeuti...
Autores principales: | Santeliz, Sonia, Caicedo, Peter, Giraldo, Elidiosmar, Alvarez, Carmen, Yustiz, María-Daniela, Rodríguez-Bonfante, Claudina, Bonfante-Rodríguez, Romina, Bonfante-Cabarcas, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572445/ https://www.ncbi.nlm.nih.gov/pubmed/28902285 http://dx.doi.org/10.1590/0074-02760160499 |
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