The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery

Legionella pneumophila infects human alveolar macrophages and is responsible for Legionnaire’s disease, a severe form of pneumonia. L. pneumophila encodes more than 300 putative effectors, which are translocated into the host cell via the Dot/Icm type IV secretion system. These effectors highjack th...

Descripción completa

Detalles Bibliográficos
Autores principales: Prevost, Marie S., Pinotsis, Nikos, Dumoux, Maud, Hayward, Richard D., Waksman, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572681/
https://www.ncbi.nlm.nih.gov/pubmed/28842705
http://dx.doi.org/10.1038/s41598-017-10249-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572681/
https://www.ncbi.nlm.nih.gov/pubmed/28842705
http://dx.doi.org/10.1038/s41598-017-10249-6

Ejemplares similares