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The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery
Legionella pneumophila infects human alveolar macrophages and is responsible for Legionnaire’s disease, a severe form of pneumonia. L. pneumophila encodes more than 300 putative effectors, which are translocated into the host cell via the Dot/Icm type IV secretion system. These effectors highjack th...
Autores principales: | Prevost, Marie S., Pinotsis, Nikos, Dumoux, Maud, Hayward, Richard D., Waksman, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572681/ https://www.ncbi.nlm.nih.gov/pubmed/28842705 http://dx.doi.org/10.1038/s41598-017-10249-6 |
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