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Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation

Sulfur mustard (SM) is a chemical warfare agent and a terrorism choice that targets various organs and tissues, especially lung tissues. Its toxic effects are tightly associated with oxidative stress. The signaling molecule hydrogen sulfide (H(2)S) protects the lungs against oxidative stress and act...

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Detalles Bibliográficos
Autores principales: Meng, Wenqi, Pei, Zhipeng, Feng, Yongwei, Zhao, Jie, Chen, Yongchun, Shi, Wenwen, Xu, Qingqiang, Lin, Fengwu, Sun, Mingxue, Xiao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572733/
https://www.ncbi.nlm.nih.gov/pubmed/28842592
http://dx.doi.org/10.1038/s41598-017-09648-6