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Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation
Sulfur mustard (SM) is a chemical warfare agent and a terrorism choice that targets various organs and tissues, especially lung tissues. Its toxic effects are tightly associated with oxidative stress. The signaling molecule hydrogen sulfide (H(2)S) protects the lungs against oxidative stress and act...
Autores principales: | Meng, Wenqi, Pei, Zhipeng, Feng, Yongwei, Zhao, Jie, Chen, Yongchun, Shi, Wenwen, Xu, Qingqiang, Lin, Fengwu, Sun, Mingxue, Xiao, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572733/ https://www.ncbi.nlm.nih.gov/pubmed/28842592 http://dx.doi.org/10.1038/s41598-017-09648-6 |
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