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Protective Effect of Val(129)-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease
Bovine spongiform encephalopathy (BSE) is the only known zoonotic prion that causes variant Creutzfeldt-Jakob disease (vCJD) in humans. The major risk determinant for this disease is the polymorphic codon 129 of the human prion protein (Hu-PrP), where either methionine (Met(129)) or valine (Val(129)...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572891/ https://www.ncbi.nlm.nih.gov/pubmed/28820136 http://dx.doi.org/10.3201/eid2309.161948 |