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Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis

Matrix metalloproteinases (MMPs) are considered important in articular cartilage breakdown during osteoarthritis (OA). Similarly, the endocannabinoid system (ECS) is implicated in joint function and modulation of nociceptive processing. Functional interplay between ECS and MMPs has been recently ind...

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Detalles Bibliográficos
Autores principales: Pajak, Agnieszka, Kostrzewa, Magdalena, Malek, Natalia, Korostynski, Michal, Starowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573042/
https://www.ncbi.nlm.nih.gov/pubmed/28860852
http://dx.doi.org/10.2147/JPR.S132682