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Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis
Matrix metalloproteinases (MMPs) are considered important in articular cartilage breakdown during osteoarthritis (OA). Similarly, the endocannabinoid system (ECS) is implicated in joint function and modulation of nociceptive processing. Functional interplay between ECS and MMPs has been recently ind...
Autores principales: | Pajak, Agnieszka, Kostrzewa, Magdalena, Malek, Natalia, Korostynski, Michal, Starowicz, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573042/ https://www.ncbi.nlm.nih.gov/pubmed/28860852 http://dx.doi.org/10.2147/JPR.S132682 |
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