Silica nanoparticles induce liver fibrosis via TGF-β(1)/Smad3 pathway in ICR mice

The liver is one of the target organs of silica nanoparticles (SiO(2) NPs) but the toxic mechanism on the liver still remains unclear. This study aimed to explore the hepatic toxicity and its mechanism through repeated intravenous exposure to SiO(2) NPs in ICR mice. Results indicated that SiO(2) NPs...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Duan, Junchao, Li, Yang, Li, Yanbo, Jing, Li, Yang, Man, Wang, Ji, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573053/
https://www.ncbi.nlm.nih.gov/pubmed/28860765
http://dx.doi.org/10.2147/IJN.S132304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573053/
https://www.ncbi.nlm.nih.gov/pubmed/28860765
http://dx.doi.org/10.2147/IJN.S132304

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