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Increased risk of breast cancer in neurofibromatosis type 1: current insights

Neurofibromatosis type 1 (NF1) is an autosomal dominant condition caused by mutation/deletion of the NF1 gene. The gene product, neurofibromin, is a tumor suppressor which represses the activity of the Ras oncogene. Central nervous system (CNS) tumors have long been associated with NF1, but their as...

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Detalles Bibliográficos
Autores principales: Howell, Sacha J, Hockenhull, Kimberley, Salih, Zena, Evans, D Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573065/
https://www.ncbi.nlm.nih.gov/pubmed/28860858
http://dx.doi.org/10.2147/BCTT.S111397