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pFAK-Y397 overexpression as both a prognostic and a predictive biomarker for patients with metastatic osteosarcoma

Focal adhesion kinase (FAK) is important for tumor cell survival and metastasis in various cancers. However, its expression and prognostic value in patients with metastatic osteosarcoma remain unknown. We investigated the expression of FAK and its phosphorylated form (pFAK-Y397) in osteosarcoma tiss...

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Detalles Bibliográficos
Autores principales: Thanapprapasr, Kamolrat, Nartthanarung, Adisak, Thanapprapasr, Duangmani, Jinawath, Artit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573209/
https://www.ncbi.nlm.nih.gov/pubmed/28846700
http://dx.doi.org/10.1371/journal.pone.0182989