Plasmid stability analysis based on a new theoretical model employing stochastic simulations

Here, we present a simple theoretical model to study plasmid stability, based on one input parameter which is the copy number of plasmids present in a host cell. The Monte Carlo approach was used to analyze random fluctuations affecting plasmid replication and segregation leading to gradual reductio...

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Detalles Bibliográficos
Autores principales: Werbowy, Olesia, Werbowy, Sławomir, Kaczorowski, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573283/
https://www.ncbi.nlm.nih.gov/pubmed/28846713
http://dx.doi.org/10.1371/journal.pone.0183512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573283/
https://www.ncbi.nlm.nih.gov/pubmed/28846713
http://dx.doi.org/10.1371/journal.pone.0183512

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