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Plasmid stability analysis based on a new theoretical model employing stochastic simulations
Here, we present a simple theoretical model to study plasmid stability, based on one input parameter which is the copy number of plasmids present in a host cell. The Monte Carlo approach was used to analyze random fluctuations affecting plasmid replication and segregation leading to gradual reductio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573283/ https://www.ncbi.nlm.nih.gov/pubmed/28846713 http://dx.doi.org/10.1371/journal.pone.0183512 |