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Association between statin use, the vaginal microbiome, and Gardnerella vaginalis vaginolysin-mediated cytotoxicity

BACKGROUND: Bacterial vaginosis (BV) is the leading dysbiosis of the vaginal microbiome. The pathways leading towards the development of BV are not well understood. Gardnerella vaginalis is frequently associated with BV. G. vaginalis produces the cholesterol-dependent cytolysin (CDC), vaginolysin, w...

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Detalles Bibliográficos
Autores principales: Abdelmaksoud, Abdallah A., Girerd, Philippe H., Garcia, Erin M., Brooks, J. Paul, Leftwich, Lauren M., Sheth, Nihar U., Bradley, Steven P., Serrano, Myrna G., Fettweis, Jennifer M., Huang, Bernice, Strauss, Jerome F., Buck, Gregory A., Jefferson, Kimberly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573284/
https://www.ncbi.nlm.nih.gov/pubmed/28846702
http://dx.doi.org/10.1371/journal.pone.0183765