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Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K(+) sensing coupled to Ca(2+) signaling and stress survival

The malaria parasite Plasmodium falciparum is exposed, during its development, to major changes of ionic composition in its surrounding medium. We demonstrate that the P. falciparum serpentine-like receptor PfSR25 is a monovalent cation sensor capable of modulating Ca(2+) signaling in the parasites....

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Detalles Bibliográficos
Autores principales: Moraes, Miriam S., Budu, Alexandre, Singh, Maneesh K., Borges-Pereira, Lucas, Levano-Garcia, Julio, Currà, Chiara, Picci, Leonardo, Pace, Tomasino, Ponzi, Marta, Pozzan, Tullio, Garcia, Célia R. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573319/
https://www.ncbi.nlm.nih.gov/pubmed/28842684
http://dx.doi.org/10.1038/s41598-017-09959-8