Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype

Cyclooxygenase-2 (COX-2) triggers pro-inflammatory processes that can aggravate neuronal degeneration and functional impairments in many neurological conditions, mainly via producing prostaglandin E2 (PGE(2)) that activates four membrane receptors, EP1-EP4. However, which EP receptor is the culprit...

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Detalles Bibliográficos
Autores principales: Kang, Xu, Qiu, Jiange, Li, Qianqian, Bell, Katherine A., Du, Yifeng, Jung, Da Woon, Lee, Jae Yeol, Hao, Jiukuan, Jiang, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573328/
https://www.ncbi.nlm.nih.gov/pubmed/28842681
http://dx.doi.org/10.1038/s41598-017-09528-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573328/
https://www.ncbi.nlm.nih.gov/pubmed/28842681
http://dx.doi.org/10.1038/s41598-017-09528-z

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