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Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype
Cyclooxygenase-2 (COX-2) triggers pro-inflammatory processes that can aggravate neuronal degeneration and functional impairments in many neurological conditions, mainly via producing prostaglandin E2 (PGE(2)) that activates four membrane receptors, EP1-EP4. However, which EP receptor is the culprit...
Autores principales: | Kang, Xu, Qiu, Jiange, Li, Qianqian, Bell, Katherine A., Du, Yifeng, Jung, Da Woon, Lee, Jae Yeol, Hao, Jiukuan, Jiang, Jianxiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573328/ https://www.ncbi.nlm.nih.gov/pubmed/28842681 http://dx.doi.org/10.1038/s41598-017-09528-z |
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