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Perfused Three-dimensional Organotypic Culture of Human Cancer Cells for Therapeutic Evaluation
Pharmaceutical research requires pre-clinical testing of new therapeutics using both in-vitro and in-vivo models. However, the species specificity of non-human in-vivo models and the inadequate recapitulation of physiological conditions in-vitro are intrinsic weaknesses. Here we show that perfusion...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573358/ https://www.ncbi.nlm.nih.gov/pubmed/28842598 http://dx.doi.org/10.1038/s41598-017-09686-0 |