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Structure-based drug discovery for combating influenza virus by targeting the PA–PB1 interaction

Influenza virus infections are serious public health concerns throughout the world. The development of compounds with novel mechanisms of action is urgently required due to the emergence of viruses with resistance to the currently-approved anti-influenza viral drugs. We performed in silico screening...

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Detalles Bibliográficos
Autores principales: Watanabe, Ken, Ishikawa, Takeshi, Otaki, Hiroki, Mizuta, Satoshi, Hamada, Tsuyoshi, Nakagaki, Takehiro, Ishibashi, Daisuke, Urata, Shuzo, Yasuda, Jiro, Tanaka, Yoshimasa, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573363/
https://www.ncbi.nlm.nih.gov/pubmed/28842649
http://dx.doi.org/10.1038/s41598-017-10021-w