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Methylseleninic Acid Provided at Nutritional Selenium Levels Inhibits Angiogenesis by Down-regulating Integrin β3 Signaling

Targeting angiogenesis has emerged as a promising strategy for cancer treatment. Methylseleninic acid (MSA) is a metabolite of selenium (Se) in animal cells that exhibits anti-oxidative and anti-cancer activities at levels exceeding Se nutritional requirements. However, it remains unclear whether MS...

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Detalles Bibliográficos
Autores principales: Cai, Zhihui, Dong, Liangbo, Song, Chengwei, Zhang, Yanqing, Zhu, Chenghui, Zhang, Yibo, Ling, Qinjie, Hoffmann, Peter R., Li, Jun, Huang, Zhi, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573405/
https://www.ncbi.nlm.nih.gov/pubmed/28842587
http://dx.doi.org/10.1038/s41598-017-09568-5