Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage

Pepcan-12 (RVD-hemopressin; RVDPVNFKLLSH) is the major peptide of a family of endogenous peptide endocannabinoids (pepcans) shown to act as negative allosteric modulators (NAM) of cannabinoid CB1 receptors. Noradrenergic neurons have been identified to be a specific site of pepcan production. Howeve...

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Detalles Bibliográficos
Autores principales: Petrucci, Vanessa, Chicca, Andrea, Glasmacher, Sandra, Paloczi, Janos, Cao, Zongxian, Pacher, Pal, Gertsch, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573408/
https://www.ncbi.nlm.nih.gov/pubmed/28842619
http://dx.doi.org/10.1038/s41598-017-09808-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573408/
https://www.ncbi.nlm.nih.gov/pubmed/28842619
http://dx.doi.org/10.1038/s41598-017-09808-8

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