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Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis

Lung resident memory T cells (T(RM)) characterized by selective expression of mucosal integrins VLA-1 (α1β1) and CD103 (α(E)β7) are generated following primary respiratory viral infections. Despite recent progress, the generation of lung T(RM) and the role of mucosal integrins following viral vector...

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Detalles Bibliográficos
Autores principales: Haddadi, Siamak, Thanthrige-Don, Niroshan, Afkhami, Sam, Khera, Amandeep, Jeyanathan, Mangalakumari, Xing, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573413/
https://www.ncbi.nlm.nih.gov/pubmed/28842633
http://dx.doi.org/10.1038/s41598-017-09909-4