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miRNA Enriched in Human Neuroblast Nuclei Bind the MAZ Transcription Factor and Their Precursors Contain the MAZ Consensus Motif

While the cytoplasmic function of microRNA (miRNA) as post-transcriptional regulators of mRNA has been the subject of significant research effort, their activity in the nucleus is less well characterized. Here we use a human neuronal cell model to show that some mature miRNA are preferentially enric...

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Detalles Bibliográficos
Autores principales: Goldie, Belinda J., Fitzsimmons, Chantel, Weidenhofer, Judith, Atkins, Joshua R., Wang, Dan O., Cairns, Murray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573442/
https://www.ncbi.nlm.nih.gov/pubmed/28878619
http://dx.doi.org/10.3389/fnmol.2017.00259