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Optimal Translation Along a Circular mRNA

The ribosome flow model on a ring (RFMR) is a deterministic model for ribosome flow along a circularized mRNA. We derive a new spectral representation for the optimal steady-state production rate and the corresponding optimal steady-state ribosomal density in the RFMR. This representation has severa...

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Detalles Bibliográficos
Autores principales: Zarai, Yoram, Ovseevich, Alexander, Margaliot, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573536/
https://www.ncbi.nlm.nih.gov/pubmed/28842606
http://dx.doi.org/10.1038/s41598-017-09602-6