AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA

Cytosolic DNAs derived from retrotransposons serve as pathogen-associated molecular patterns for pattern recognition receptors (PRRs) that stimulate the induction of interferons (IFNs) and other cytokines, leading to autoimmune disease. Cyclic GMP-AMP synthase is one PRR that senses retrotransposon...

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Detalles Bibliográficos
Autores principales: Nakaya, Yuki, Lilue, Jingtao, Stavrou, Spyridon, Moran, Eileen A., Ross, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573678/
https://www.ncbi.nlm.nih.gov/pubmed/28679751
http://dx.doi.org/10.1128/mBio.00944-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573678/
https://www.ncbi.nlm.nih.gov/pubmed/28679751
http://dx.doi.org/10.1128/mBio.00944-17

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